Business Areas

DNAVEC develops products targeting the projects mentioned below and undertakes technological cooperation and/or technological services etc within a field of vision of the practical use of our original vector platform technology. Among those projects, the gene therapy project and vaccine project include pipelines to just before clinical trial and are already under negotiation for technology transfer.

Gene Therapy

Our company confronts gene therapy, expected to be a core medical technology this century. Our aim is to realize a much higher therapeutic effect on target diseases through means of our vector carrying disease-related genes. Gene therapy medicines using our new vectors hold the possibility of excelling over existing vectors and overcoming diseases incurable at this stage. Target diseases that we are planning to develop relevant vectors for are as follows:

Target Diseases

Circulation system: Severe Ischemic Limb, angina pectoris, atherosclerosis
Respiratory system: Cystic fibrosis
Musculoskeletal system: Chronic articular rheumatism
Ophthalmic system: Retina-degeneration diseases (Retinitis pigmentosa, diabetic retinopathy, etc.)
Cancer: Brain tumors, etc.

Gene Vaccines

Our company is developing gene vaccines using the SeV vectors. The gene vaccines of our company are RNA VACCINES, not DNA vaccines, and thought to be applicable in a wide variety of infectious diseases etc because our RNA vaccines are thought to be free of genetic side effects. Gene vaccines improve iimmune responses against diseases by means of the administration of a vector carrying therapeutic antigen genes etc. We are evaluating the therapeutic benefits through this vector function against such infectious diseases as AIDS, SARS, and cancer as well .

Target Diseases

AIDS
SARS
Cancer

Function-Analysis of Genes and Proteins

We are in the era of the post-genome. There is increasing needs for the function- analysis of new genes, lead by genome analysis and SNPS analysis. The analysis of new functions of known proteins is also becoming essential objects of researches. The high ability of gene transfer and gene expression of our SeV vectors at both the in vitro and in vivo levels will play an optimal role in these studies. Our company offers any vectors carrying the desired genes for the purpose of function- analysis. Business expansion to new drug generation would be highly possible

Preparation/manufacturing Recombinant Proteins

Our company prepares/manufactures recombinant proteins and antibodies using our excellent vector technology. These materials can be used in basic researches and for the verification of new functions of proteins and/or the discovery of new functions of existing known proteins. Our company offers possibilities leading to new drug generation along with the promotion of such researches using our vectors.