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What is a vector?
The word vector means “carrier” and denotes material with the function of transporting a therapeutic gene into certain target cells. The efficiency of the technology that transfers the gene into the cells is a key condition for gene therapy to be a success. Therefore, it may safely be said that, “The vector is indeed the basic technology for gene therapy”.
Up to date, several vectors have been used in clinical researches. For example, there are viral vectors that have been altered from existing viruses such as the retrovirus, adenovirus, adeno-associated virus etc and artificial non-viral vectors such as liposomes etc. However, they are only limited member of vectors ,even though there have been many trials carried out to produce various vectors in the basic research phase.
Moreover, it has been pointed out that most of the clinical trials using these existing vectors show insufficient therapeutic resultsy, and in addition some of the trials caused safety concern about these vectors.
Researches in relation to the improvement of existing vectors and creation of new vectors are being powerfully done throughout the world. Especially, it has been demonstrated in animal experiments etc that our SeV vector is a high performer in resolving the disadvantages of existing vectors on therapeutic efficacy and safety. It could be said that the vector has the potential to be the global standard of coming age.
